Package: RsqMed Title: Total Mediation Effect Size Measure for High-Dimensional Mediators Version: 1.1 Authors@R: c( person(given = "Tianzhong", family = "Yang", role = c("aut", "cre"), email = "yang3704@umn.edu"), person(given = "Chunlin", family = "Li", role = "aut", email = "chunlin@iastate.edu"), person(given = "Zhichao", family = "Xu", role = "ctb", email = "ZXu7@mdanderson.org")) Description: An implementation of calculating the R-squared measure as a total mediation effect size measure and its confidence interval for moderate- or high-dimensional mediator models. It gives an option to filter out non-mediators using variable selection methods. The original R package is directly related to the paper Yang et al (2021) "Estimation of mediation effect for high-dimensional omics mediators with application to the Framingham Heart Study" . The new version contains a choice of using cross-fitting, which is computationally faster. The details of the cross-fitting method are available in the paper Xu et al (2023) "Speeding up interval estimation for R2-based mediation effect of high-dimensional mediators via cross-fitting" . License: GPL-3 Depends: R (>= 3.5.0) Imports: SIS (>= 0.8), GMMAT (>= 1.4.1) Encoding: UTF-8 LazyData: true RoxygenNote: 7.2.3 NeedsCompilation: no Packaged: 2026-09-24 08:29:18 UTC; root Maintainer: Tianzhong Yang Author: Tianzhong Yang [aut, cre], Chunlin Li [aut], Zhichao Xu [ctb] Repository: https://ytzhong.r-universe.dev Date/Publication: 2023-11-15 02:37:51 UTC RemoteUrl: https://github.com/cran/RsqMed RemoteRef: HEAD RemoteSha: f59ed862c45af418df48f5792c01c4755d75e401